The Basics
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Sickle cell is inherited when both parents carry the sickle cell trait.
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It affects about 100,000 people in the U.S., with higher rates among African American, Hispanic, and certain ethnic communities.
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In South Carolina, more than 4,000 people live with sickle cell disease.
Resource Links:
Common Complications
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Pain crises (sudden episodes of severe pain)
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Anemia (low red blood cell count, causing fatigue)
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Infections (higher risk due to spleen problems)
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Organ damage or stroke if not managed properly
Resource Links:
School Handbook for Sickle Cell Care
Care Giver Back to School Checklist
Sickle Cell Trait
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Having one copy of the sickle cell gene is called “sickle cell trait.”
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People with the trait usually do not have symptoms, but they can pass the gene to their children.
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Trait awareness is important for family planning, athletics, and health decisions.
Resource Links:
Action Plan for Student Athletes
Disclaimer: Rise SC does not provide medical care. These resources are for educational purposes. Always consult your healthcare provider for personal medical advice.

Sickle Cell 101
Sickle cell disease (SCD) is a genetic blood disorder that affects the shape and function of red blood cells. Instead of smooth, round cells, people with SCD have cells shaped like a “sickle” or crescent. These sickled cells can block blood flow, cause pain, and lead to other health problems.
